Insulin sensitizing agents and polycystic ovary syndrome
نویسندگان
چکیده
منابع مشابه
Effects of insulin-sensitizing agents and insulin resistance in women with polycystic ovary syndrome
OBJECTIVE The aim of this study was to investigate the effect of insulin sensitizing agents on hormonal and metabolic parameters as well as menstrual patterns in women with polycystic ovary syndrome (PCOS). METHODS One hundred and twenty-three patients with PCOS were included. Metformin was administered to patients at 1,500 mg or 1,700 mg daily for 3 months. If the patients had no improvement...
متن کاملInsulin-sensitising agents in polycystic-ovary syndrome.
Insulin-sensitizing agents have been recently proposed as the therapy of choice for polycystic ovary syndrome (PCOS), since insulin resistance and associated hyperinsulinemia are recognized as important pathogenetic factors of the syndrome. Moreover, since almost all obese PCOS women and more than half of those of normal weight are insulin resistant, and therefore present some degree of hyperin...
متن کاملInsulin-sensitizing agents: use in pregnancy and as therapy in polycystic ovary syndrome.
Treatment with insulin-sensitizing agents is a relatively recent therapeutic strategy in women with polycystic ovary syndrome (PCOS) and insulin resistance. The key areas addressed in this review include PCOS and the development of type 2 diabetes mellitus and gestational diabetes, as well as the use of insulin-sensitizing agents, particularly metformin, in the management of infertility in obes...
متن کاملInsulin Resistance and Polycystic Ovary Syndrome.
BACKGROUND Insulin resistance and the associated compensatory hyperinsulinemia are common findings in women with PCOS, and may play a key role in this condition. METHODS In this article, we focused on the significance of insulin resistance in PCOS, reviewing the available literature on epidemiology, pathogenesis, pathophysiology and treatment of this condition. RESULTS It has been estimated...
متن کاملInsulin Secretory Defects in Polycystic Ovary Syndrome
The increased prevalence of non-insulin-dependent diabetes mellitus (NIDDM) among women with polycystic ovary syndrome (PCOS) has been ascribed to the insulin resistance characteristic of PCOS. This study was undertaken to determine the role of defects in insulin secretion as well as familial factors to the predisposition to NIDDM seen in PCOS. We studied three groups of women: PCOS with a fami...
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ژورنال
عنوان ژورنال: European Journal of Endocrinology
سال: 1998
ISSN: 0804-4643,1479-683X
DOI: 10.1530/eje.0.1380253